Intracerebral hemorrhaging has become one of the leading causes of death in the world, with medical professionals everywhere trying to figure out how they can prevent further human loss. All of that is about to end, however, now that stroke patients may find hope in clot-busting therapy.
Two new studies were made public yesterday at the stroke association’s annual gathering in Los Angeles and they seem to include groundbreaking revelations for the medical field.
Apparently, there is a clot-busting drug called tissue plasminogen activator (tPA), which has the ability to significantly reduce the death rate among patients suffering from hemorrhagic stroke.
The first study on this topic was conducted on 500 subjects with intraventricular hemorrhaging. The patients were administered either tPA or saline, through a brain catheter.
Their evolution was followed for five years, between 2009-2015 and the results were fascinating to say the least. As it turns out, the patients who were treated with tPA had a 10% lower risk of death.
Furthermore, 18% of the people with clots larger than 20 ml, who were treated with tPA, also presented better results than the ones treated with saline.
Last but not least, 79.8% of the patients who were administered tPA had an 80% clot removal and most of them had double chances of survival then the ones who received saline.
Dr. Isaam Awad is one of the researchers involved in this study and a professor of surgery at the University of Chicago. He says that when the trial started, there was very little knowledge about this sort of therapy and the team really did not know how or when it should be used.
Seeing the results, they now have a much better picture of what they are dealing with and they know how to use this procedure in order to obtain maximum results.
The second study, led by Dr. Daniel Hanley from John Hopkins University, links tPA to the brain’s ventricles, which also decreases the death rate by 10%.
The researchers discovered that tPA managed to clear the blood clogged in the brains of patients suffering from intraventricular hemorrhaging. When compared to a regular course of treatment, experts say this procedure is much safer, with a very low rate of a brain infection or other serious side effects.
In the initial phases, many people thought that using tPA in order to treat a bleeding stroke would only make things worse, but the results gathered from the two studies tell a different story.
Even though these results are only considered preliminary, this could definitely be a second chance at life for many people suffering from intracerebral bleeding and a cause for celebration for many of their families.
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